Description

Selective Androgen Receptor Research: S-23

S-23 is an orally bioavailable, non-steroidal selective androgen receptor modulator (SARM) developed to investigate targeted androgen receptor pathways in tissue-specific models. Characterized by high binding affinity ($K_i \approx 0.5 \text{ nM}$) for the androgen receptor, it exhibits high anabolic activity in skeletal muscle and bone tissue while demonstrating reduced androgenic effects in non-target peripheral tissues. This high selectivity makes it a valuable reference compound in metabolic, musculoskeletal, and endocrinological research.

Technical & Product Specifications

• Volume & Concentration: 30ml @ 25mg/ml (30 x 25mg | Total: 750mg)

• Purity: >99% Purity

• Molecular Weight: 416.753 g/mol

• Solubility: Polyglycols

• Storage: Store at -20℃ (up to 3 years)

• CAS No.: 1010396-29-8

Pharmacological Mechanism & Research Applications

As an investigational selective androgen receptor modulator, the chemical structure of s-23 sarm allows it to bind directly to target receptors, inducing structural conformation changes that regulate gene expression:

• Musculoskeletal Tissue Dynamics: Stimulates localized protein synthesis and nitrogen retention in myoblast cultures, aiding cellular studies on muscle atrophy and wasting models.

• Bone Mineral Density: Promotes osteoblast differentiation and mineral deposition, serving as an analytical tool for bone loss studies.

• Endocrine & Receptor Cross-Talk: Inhibits endogenous gonadotropin secretion in preclinical models, allowing researchers to evaluate feedback loops within the hypothalamic-pituitary-gonadal (HPG) axis.

Clarifying Nomenclature & Research Handling

When reviewing technical listings, researchers occasionally encounter naming ambiguities across different scientific fields. For instance, saflager s-23 refers to a dry lager brewing yeast strain used in beverage fermentation, which is entirely unrelated to small-molecule androgen receptor ligands. Similarly, referencing an s-23 peptide is a misnomer, as S-23 is a non-steroidal synthetic small molecule rather than an amino acid chain.

For analytical facilities seeking to buy s-23 for strictly in vitro laboratory experiments or reference testing, securing high-purity compounds ensures minimal baseline variability and reliable experimental data.

High-Purity Reagents by Receptor Chemicals

Receptor Chemicals provides analytical-grade research standards formulated for demanding laboratory environments. Every batch is rigorously tested for molecular integrity, purity, and freedom from unreacted synthetic precursors to support reproducible scientific outcomes.