Description
Advanced Bioenergetic Research: SLU-PP-332
SLU-PP-332 is a synthetic, small-molecule pan-agonist targeting Estrogen Receptor-Related Receptors ($\text{ERR}\alpha$, $\text{ERR}\beta$, and $\text{ERR}\gamma$). Recognized in metabolic literature as a potent exercise mimetic, it binds to ERR nuclear receptors to activate key physiological gene networks typically triggered by high-intensity endurance training. By enhancing cellular respiration and substrate oxidation without altering food intake, this small molecule serves as a critical reference standard in cellular bioenergetics and metabolic research.
Technical & Product Specifications
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Volume / Concentration: 30ml | 10,000mcg/ml ($30 \times 10,000\text{mcg}$ total yield)
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Formulation Advantage: High-density liquid formulation (10,000mcg/ml vs standard 200mcg/ml solutions)
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Chemical Name / IUPAC: 4-hydroxy-N-[(Z)-naphthalen-2-ylmethylideneamino]benzamide
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Molecular Weight (M.Wt): 290.3 g/mol
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Formula: $\text{C}_{18}\text{H}_{14}\text{N}_2\text{O}_2$
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Solubility: Soluble in Polyglycols (PEG) and organic solvents
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Purity: >99% Purity (HPLC)
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Storage: Store at -20℃ (Stable up to 3 years)
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CAS No.: 303760-60-3
Mechanism of Action & Research Applications
Unlike non-selective metabolic modifiers, slu-pp-332 directly coordinates transcription factors regulating energy expenditure across skeletal muscle, cardiac tissue, and liver pathways:
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Mitochondrial Biogenesis & Respiration: Enhances mitochondrial density, elevates oxygen consumption rates (OCR), and upregulates pyruvate dehydrogenase kinase 4 (PDK4) gene expression.
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Substrate Switching & Lipid Oxidation: Drives a metabolic transition toward fatty acid oxidation, reducing lipid accumulation in preclinical metabolic syndrome models.
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Muscle Fiber Remodeling: Promotes the conversion of fast-glycolytic muscle fibers into oxidative, endurance-type muscle fibers to increase cellular fatigue resistance.
Laboratory Handling & Catalog Classification
Although frequently cataloged in commercial research listings as a slu-pp-332 peptide, SLU-PP-332 is structurally a small-molecule benzohydrazide derivative, not an amino acid chain. Calibrating accurate slu-pp-332 dosage parameters in cell-based assays requires analytical-grade purity to avoid baseline noise and ensure experimental reproducibility.
For analytical testing facilities, bio-laboratories, and research institutions seeking to evaluate slu-pp-332 buy online options, sourcing high-concentration, high-purity compounds guarantees structural integrity and reproducible laboratory outcomes.
Sourcing High-Purity Reagents
Receptor Chemicals provides laboratory-grade compounds validated to meet rigorous analytical standards. Our high-density polyglycol liquid formulations ensure uniform solubility and batch-to-batch reliability across advanced metabolic assays.
