Description
Selective Metabolic Activation: GW-501516 (Cardarine)
GW-501516 (Cardarine) is a high-affinity, selective agonist of the peroxisome proliferator-activated receptor delta . By selectively binding to PPAR$\delta$ nuclear receptors with high potency ), it serves as an essential reference standard in bioenergetic research for studying fatty acid oxidation, skeletal muscle gene expression, and lipid metabolic pathways.
Technical & Product Specifications
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Volume & Concentration: 30ml @ 10mg/ml | (30 x 10mg)
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Molecular Weight: 453.50 g/mol
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CAS No.: 317318-70-0
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Purity: >99% (HPLC validated)
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Solubility: Polyglycols, DMSO, and Ethanol
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Biological Half-Life: ~24 hours
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Storage Conditions: Store at 20°C (3-year stability)
Pharmacological Mechanisms & Academic Research
Unlike Selective Androgen Receptor Modulators (SARMs), GW-501516 (Cardarine) operates independently of the androgen receptor pathway. Activation of upregulates proteins responsible for energy expenditure and lipid transport, such as ATP-binding cassette transporter A1 (ABCA1) and carnitine palmitoyltransferase 1 (CPT1).
Academic institutions and analytical laboratories examine this compound across several key investigative areas:
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Fatty Acid Oxidation & Substrate Utilization: Stimulates mitochondrial beta-oxidation in skeletal muscle cells, shifting cellular fuel preference from glucose utilization to fatty acids.
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Lipid Profile Regulation: Evaluates pathways involved in raising high-density lipoprotein (HDL) cholesterol while reducing small, dense low-density lipoprotein (LDL) particles and plasma triglycerides.
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Gene Expression & Muscle Fiber Transformation: Modulates transcriptional networks that govern oxidative type I muscle fiber phenotype conversion and exercise endurance gene programs.
Laboratory Sourcing & Handling Parameters
When formulating stable in vitro protocols, laboratories utilizing a high-purity solution standard require reliable polyglycol carrier vehicles to ensure complete dissolution without compound degradation.
For researchers evaluating where to buy cardarine gw-501516 liquid reagents, selecting analytical vendors with comprehensive high-performance liquid chromatography (HPLC) testing guarantees batch consistency. Institutions searching for verifiable cardarine for sale or seeking a reliable vendor to cardarine buy orders online must ensure compounds are strictly sourced as non-clinical reference materials. Finding dependable suppliers for gw-501516 for sale ensures research protocols maintain rigorous scientific standards without batch-to-batch variation.
Quality Assurance by Receptor Chemicals
Receptor Chemicals delivers high-purity laboratory reagents manufactured under strict analytical standards. Every unit undergoes rigorous LC-MS and HPLC verification to provide verified molecular integrity, chemical stability, and reproducible results for advanced metabolic research protocols.
