Description

Non-Steroidal Androgen Modulator Research: MK-2866 (Ostarine)

MK-2866 (Ostarine), chemically designated as Enobosarm, is a landmark non-steroidal selective androgen receptor modulator (SARM). It was developed to bind directly to the androgen receptor with high selectivity, mimicking anabolic activity in targeted tissues such as skeletal muscle and bone while minimizing secondary androgenic effects in non-target organs. As a result, it serves as an indispensable reference compound in pre-clinical investigations evaluating muscle-wasting conditions, sarcopenia, and androgen signaling pathways.

Technical & Product Specifications

• Sample Size: 30ml @ 25mg/ml | (30 x 25mg)

• Molecular Weight: 389.33 g/mol

• Chemical IUPAC Name: ((2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide)

• Purity: >99% (HPLC validated)

• Solubility: Soluble in Polyglycols, DMSO, and Ethanol

• Half-Life: ~24 hours

• Storage Conditions: Store at 20°C (3-year stability)

• CAS No.: 841205-47-8

Pharmacological Mechanisms & Academic Applications

Unlike traditional anabolic steroids, ostarine (mk-2866) does not undergo $5\alpha$-reduction to DHT-like compounds, nor does it serve as a substrate for aromatase-mediated conversion into estrogenic metabolites. By acting as a tissue-selective partial agonist, it facilitates precise structural research in bio-analytical settings:

• Muscle Mass Retention & Myogenesis: Activates transcription factors responsible for protein synthesis in myoblasts, providing insights into baseline catabolic suppression.

• Bone Mineral Density Kinetics: Stimulates osteoblast activity, assisting in the evaluation of skeletal restoration and bone turnover markers.

• Receptor Affinity Profiles: Functions as a control standard for measuring ligand-binding domain kinetics across androgenic targets.

Laboratory Handling & Vendor Standards

Establishing standardized quantitative protocols requires analytical-grade purity. Assays involving ostarine mk-2866 depend on verified concentration parameters to preserve trial accuracy and prevent cross-contamination in cell culture systems.

When investigating mk-2866 for sale options for institutional research, choosing verified vendors ensures batch-to-batch consistency and structural confirmation via mass spectrometry. Evaluating mk-2866 catalog listings from certified chemical suppliers provides laboratories with raw materials explicitly labeled and tested for non-clinical, analytical applications.

Quality Assurance by Receptor Chemicals

Receptor Chemicals provides high-purity reference reagents designed to meet rigorous research parameters. Every batch undergoes HPLC and mass spectrometry testing to ensure consistent molecular integrity across all bioenergetic and anabolic receptor studies.