Description

Advanced Neuropeptide Research: DSIP

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring well-researched amphiphilic nonapeptide first isolated from the cerebral venous blood of rabbits in a somnolent state. Found within the central nervous system, hypothalamus, and peripheral tissues, this regulatory neuropeptide plays a fundamental role in modulating endocrine functions, stress-response pathways, and central neuronal activity. Sourcing high-purity reference materials is essential for laboratories investigating peptide-mediated endocrine dynamics and central nervous system signaling.

Technical & Product Specifications

• Quantity: 10mg Lyophilized Powder

• Purity: >99% (HPLC Verified)

• Molecular Weight: ~848.81 g/mol

• Storage: Store desiccated at -20℃ (stable for up to 3 years)

• CAS No.: 62568-57-4

Mechanism of Action and Research Significance

As a highly specialized regulatory compound, the dsip peptide exhibits a unique multi-target profile in cellular and animal models:

• Neuromodulation & Sleep Architecture: Unlike typical sedative agents, it modulates slow-wave (delta) sleep patterns and motor activity without disrupting normal physiological REM cycles.

• Endocrine Regulation: Interacts with the hypothalamic-pituitary-adrenal (HPA) axis to modulate adrenocorticotropic hormone (ACTH) and luteinizing hormone (LH) secretion, serving as a key model for stress-response attenuation.

• Neuroprotection & Antioxidant Signaling: Demonstrates cellular protection against oxidative stress, reducing excitotoxicity by modulating glutamate receptor sensitivity.

Laboratory Handling and Protocol Standards

When designing experimental assays, determining accurate dsip peptide dosage parameters and reconstitution procedures is critical to maintaining peptide stability and ensuring reproducible data. Determining the correct experimental dsip dosage across varied cell lines or in vivo models depends heavily on stock solution preparation and handling protocols. Utilizing premium-grade dsip peptide 10mg 99% lab tested vials ensures that researchers can conduct multi-well assays without background interference from synthesis byproducts or degraded sequences.

Premium Chemical Sourcing

For biopharmaceutical facilities, academic institutes, and analytical research teams, Receptor Chemicals offers premium-grade neuropeptides produced under strict quality standards. Each batch undergoes rigorous HPLC and mass spectrometry verification to guarantee chemical purity, structural consistency, and reliable analytical performance.