Description

Non-Steroidal Antiandrogen Research: RU58841

RU58841 (IUPAC: 4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile) is a potent non-steroidal antiandrogen specifically designed to investigate localized androgen receptor dynamics. Operating as a competitive receptor antagonist, it binds directly to target androgen receptors to inhibit local dihydrotestosterone (DHT) and testosterone interactions without altering systemic hormone secretion or serum gonadotropin levels. This precise localized selectivity makes it an essential reference compound in androgenetic alopecia, sebaceous gland activity, and dermatological bioenergetic research.

Technical & Product Specifications

• Volume & Concentration: 30ml | 50mg/ml | 5% (30 x 50mg total)

• Purity: >99% Purity

• Molecular Weight (M.Wt): 369.34 g/mol

• CAS No.: 154992-24-2

• Half-Life: 24 hours

• Solubility: Polyglycols, Aqua, Ethanol

• Storage: Store at 5°C (Stable up to 3 years)

Selective Receptor Antagonism in Research

Unlike systemic androgen receptor blockers that alter circulating hormone profiles, this synthetic compound demonstrates high affinity for target tissue androgen receptors:

• Localized Receptor Occupancy: Prevents DHT-induced transcriptional changes within follicular tissue, protecting cellular structures from androgenic miniaturization.

• Sebaceous Gland Modulation: Inhibits androgen-stimulated lipid production in human sebocyte cell models, aiding acne pathophysiology studies.

• Follicular Kinetics: Promotes the transition of hair follicles from the involution phase back into active growth phases in preclinical models.

Laboratory Sourcing & Handling Standards

Although cataloged occasionally under inaccurate search terms like ru58841 peptide, it is structurally a non-steroidal hydantoin derivative rather than an amino acid chain. When preparing experimental liquid solutions or reconstituting raw ru58841 powder, researchers benefit from its reliable solubility across polyglycols, aqua, and ethanol vehicles.

For academic laboratories and research facilities exploring ru58841 buy channels or identifying verified ru58841 for sale listings, obtaining high-purity, stable solutions ensures accurate receptor binding assays, minimal baseline noise, and consistent batch-to-batch reproducibility.

Analytical Reagents by Receptor Chemicals

Receptor Chemicals provides high-purity research compounds engineered to meet rigorous scientific criteria. Every batch undergoes strict quality verification to ensure verified molecular integrity, reliable 24-hour half-life stability, and complete compliance across demanding laboratory applications.