Description

Endogenous Neuropeptide Research: VIP

VIP (Vasoactive Intestinal Peptide) is a naturally occurring, 28-amino acid neuropeptide synthesized in the central nervous system, gastrointestinal tract, and cardiovascular system. Operating as a selective high-affinity agonist for the VPAC1 and VPAC2 G-protein coupled receptors, it plays an instrumental role in mediating vasodilation, smooth muscle relaxation, bronchial dynamics, and anti-inflammatory pathways. High-purity reference peptides are essential tools for research facilities exploring pulmonary physiology, neuroimmunology, and cellular signaling networks.

Technical & Product Specifications

• Sample Size: 5mg

• Purity: >99% Purity

• Molecular Weight (M.Wt): ~3,325.8 g/mol

• Storage: Store at -20℃ (up to 3 years)

• Half-Life: Rapidly metabolized in vivo

• CAS No.: 37221-79-7

(Note: Supplied as a sterile lyophilized powder requiring reconstitution prior to laboratory use. Sterile water for reconstitution is available separately.)

Key Signaling Mechanisms in Biochemical Research

Investigating the biological scope of the vip peptide highlights its diverse functional roles across multiple physiological systems:

• VPAC Receptor Signaling: Triggers intracellular cAMP accumulation via adenylate cyclase stimulation upon receptor activation.

• Immunomodulation & Inflammation: Modulates cytokine production by suppressing pro-inflammatory mediators (such as TNF-$\alpha$ and IL-6) while promoting regulatory T-cell differentiation.

• Pulmonary & Vascular Dynamics: Induces potent relaxation of vascular and bronchial smooth muscle, serving as a primary target in respiratory system models.

Laboratory Protocols and Assay Sourcing

When preparing cell culture or binding assays, calculating accurate vip peptide dosage parameters and maintaining exact reconstitution ratios ensures reliable quantitative outputs. Laboratories requiring analytical consistency often acquire high-purity stock batches to eliminate variations across trial series. Determining where to buy vip peptide compounds with certified third-party testing guarantees structural integrity, zero cross-contamination, and reproducible experimental results. For research institutions searching for premium vip peptide for sale, sourcing lyophilized powder with low endotoxin levels is crucial for maintaining cellular viability.

High-Purity Analytical Solutions

Receptor Chemicals provides analytical-grade research reagents engineered to satisfy demanding scientific specifications. Every lot undergoes rigorous HPLC and mass spectrometry verification to confirm identity, purity, and long-term stability for academic and industrial research laboratories.